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Search Term: Medical Sciences

Technologies


Selective Brain Cooling Technology
Background Brain cooling (hypothermia) has been shown to prevent brain injury (neuroprotection) from stroke, brain trauma and cardiac arrest in both animal models and patient studies. Currently, the main hurdles in the clinical application of hypothermia are: 1) most brain cooling methods also cool down the rest of the body with its associated comp...
Training System for Ear Pathologies
Background: Otolaryngology is the study and treatment of disorders of the ear, nose, and throat (ENT). Otoscopy is the visual examination of the ear canal and eardrum using an instrument called an otoscope for the purpose of diagnosing disease. It is routinely performed by primary caregivers, audiologists and surgeons. At present, trainees are taug...
The Desired Sensation Level Multi-stage [i/o] Algorithm
The Desired Sensation Level: DSL [i/o] algorithm was released to manufacturers in the late 1990s in the form of a dynamic loadable/linked library (DLL). We appreciate your support and want you to know that the money that we have received from manufacturers in the form of license fees for the DLL is put back into research, development and technical ...
miR-195 Antagomir Treatment of Sepsis
Background: MicroRNAs (miRNAs) are small non-coding RNA molecules encoded by eukaryotic nuclear DNA, on average 22 nucleotides long, that function in transcriptional and post-transcriptional regulation of gene expression via base-pairing with complementary sequences within mRNA molecules, usually resulting in gene silencing via translational repre...
Food-Grade Bacteria Species to Detoxify and Remove Heavy Metals from Humans
Background: There are many heavy metals in our environment, both naturally and from pollution. The term "heavy metal" applies to a group of metals with similar chemical properties. Some of these, including copper, iron and zinc, play important roles in our bodies, while others can have toxic effects. Examples of these are lead, which is found in p...
Peptides targeting EGFL7, a critical player in angiogenesis
Background: Epidermal growth factor-like 7 (EGFL7) is an endothelial cell secreted protein whose expression is restricted to actively remodeling vascular endothelium. It is critical for vascular tube formation during angiogenesis through localizing to the extracellular matrix (ECM) at the basal surface of endothelial cells and promoting endothelial...
Kinetic Deconvolution Optical Reconstruction Algorithm (KDOR) for retrieving multiregional hemodynamic parameters from optical measurements
Background: Dynamic contrast enhanced (DCE) methods can be used in biomedical optics to measure the kinetic properties of tissue, such as blood flow, blood volume, leakage and receptor density. Similar to DCE methods in computed tomography, magnetic resonance imaging or positron emission tomography, the injection of an optical dye is required. Conv...
Keywords Cancer, Imaging
Category Medical Sciences
EGFR antagonist-mediated prevention of post myocardial infarction ruptures
Background: Cardiovascular disease is a leading cause of death worldwide, claiming the lives of an estimated 17 million people annually. Myocardial infarctions (MI), or heart attacks, are a leading cause of mortality and morbidity. Complications following MI include maladaptive left ventricle (LV) tissue remodeling and cardiac rupture. Cardiac rupt...
Bone Marrow Derived Cells That Stimulate Pancreatic Regeneration in Type II Diabetes
Background: Diabetes affects over 18M Americans with almost 90% of these being attributed to environmental factors and lifestyle decisions. In the United States and Europe alone, the number of type II diabetes patients is expected to rise to ~41.5M by 2012. In contrast to type I diabetes, in type II diabetes the individual genetics of pancreas func...
Anti-Infective Efficacy of Histatin-Related Peptide DB2121
Background: In order to maximize resources, biological systems are designed to generate multifunction protein units that serve different roles depending upon need and context. In particular, there are several families of proteins that have emerged with both antimicrobial properties, as well as bi-activity to promote wound closure and healing. Funga...

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