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The Desired Sensation Level Multi-stage [i/o] Algorithm
The Desired Sensation Level: DSL [i/o] algorithm was released to manufacturers in the late 1990s in the form of a dynamic loadable/linked library (DLL). We appreciate your support and want you to know that the money that we have received from manufacturers in the form of license fees for the DLL is put back into research, development and technical ...
Published: Nov 28, 2013
Keywords(s): Audiology, Computer Software, Pediatric, Therapeutics/Intervention
Category(s): Medical Sciences
miR-195 Antagomir Treatment of Sepsis
Background: MicroRNAs (miRNAs) are small non-coding RNA molecules encoded by eukaryotic nuclear DNA, on average 22 nucleotides long, that function in transcriptional and post-transcriptional regulation of gene expression via base-pairing with complementary sequences within mRNA molecules, usually resulting in gene silencing via translational repre...
Published: Aug 27, 2013
Keywords(s): Therapeutics/Intervention, Sepsis
Category(s): Medical Sciences
Food-Grade Bacteria Species to Detoxify and Remove Heavy Metals from Humans
Background: There are many heavy metals in our environment, both naturally and from pollution. The term "heavy metal" applies to a group of metals with similar chemical properties. Some of these, including copper, iron and zinc, play important roles in our bodies, while others can have toxic effects. Examples of these are lead, which is found in p...
Published: Apr 9, 2013
Keywords(s): Bioremediation, Pesticides, Probiotics, Green Energy & Environmental Remediation
Category(s): Medical Sciences, Agricultural & Biological Sciences
Peptides targeting EGFL7, a critical player in angiogenesis
Background: Epidermal growth factor-like 7 (EGFL7) is an endothelial cell secreted protein whose expression is restricted to actively remodeling vascular endothelium. It is critical for vascular tube formation during angiogenesis through localizing to the extracellular matrix (ECM) at the basal surface of endothelial cells and promoting endothelial...
Published: Oct 30, 2012
Keywords(s): Imaging, Peptides, Cancer, Therapeutics/Intervention, Angiogenesis/Vasculogenesis, Epidermal Growth Factor, Macular Degeneration, Diabetes/Renal/Hepatic
Category(s): Medical Sciences
Kinetic Deconvolution Optical Reconstruction Algorithm (KDOR) for retrieving multiregional hemodynamic parameters from optical measurements
Background: Dynamic contrast enhanced (DCE) methods can be used in biomedical optics to measure the kinetic properties of tissue, such as blood flow, blood volume, leakage and receptor density. Similar to DCE methods in computed tomography, magnetic resonance imaging or positron emission tomography, the injection of an optical dye is required. Conv...
Published: Sep 27, 2012
Keywords(s): Cancer, Imaging
Category(s): Medical Sciences
EGFR antagonist-mediated prevention of post myocardial infarction ruptures
Background: Cardiovascular disease is a leading cause of death worldwide, claiming the lives of an estimated 17 million people annually. Myocardial infarctions (MI), or heart attacks, are a leading cause of mortality and morbidity. Complications following MI include maladaptive left ventricle (LV) tissue remodeling and cardiac rupture. Cardiac rupt...
Published: Aug 17, 2012
Keywords(s): Cardiovascular, Epidermal Growth Factor, Ischemia/Reperfusion
Category(s): Medical Sciences
Therapeutic Agent for Improvement of Wound Healing
Background: Chronic wounds are a major source of morbidity and mortality in many disciplines of clinical medicine. Nearly 40 million wound patients in North America alone generate annual costs for care in excess of $16 billion. Wound healing involves a series of integrated physiological processes. However, these processes are not only complex but f...
Published: Feb 9, 2012
Keywords(s): Wound, Diabetes/Renal/Hepatic, Dermatology, Therapeutics/Intervention, Infection/Infectious Disease
Category(s): Medical Sciences
Bone Marrow Derived Cells That Stimulate Pancreatic Regeneration in Type II Diabetes
Background: Diabetes affects over 18M Americans with almost 90% of these being attributed to environmental factors and lifestyle decisions. In the United States and Europe alone, the number of type II diabetes patients is expected to rise to ~41.5M by 2012. In contrast to type I diabetes, in type II diabetes the individual genetics of pancreas func...
Published: Feb 8, 2012
Keywords(s): Therapeutics/Intervention, Stem Cells/Regenerative Medicine, Diabetes/Renal/Hepatic, Inflammation
Category(s): Medical Sciences
Anti-Infective Efficacy of Histatin-Related Peptide DB2121
Background: In order to maximize resources, biological systems are designed to generate multifunction protein units that serve different roles depending upon need and context. In particular, there are several families of proteins that have emerged with both antimicrobial properties, as well as bi-activity to promote wound closure and healing. Funga...
Published: Feb 8, 2012
Keywords(s): Wound, Therapeutics/Intervention, Peptides, Allergy/Immunology, Cancer, Dermatology, HIV, Surgery, Transplantation, Infection/Infectious Disease
Category(s): Medical Sciences
High Precision Radiostereometric Analysis (RSA) System for Monitoring Micro-Movement in Orthopedic Implants
Background: Over 400,000 people per year in the United States undergo joint replacement surgery comprising a range of implant types and locations. These surgeries include the hip, knee, spine and digital/wrist. It has been well established that short-term micromotion at the implant-bone interface can be a strong predictor of long-term implant loose...
Published: Feb 8, 2012
Keywords(s): Computer Software, Diagnostics, Imaging, Musculoskeletal, Surgery
Category(s): Medical Sciences

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