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Search Term: cardiovascular


EGFR antagonist-mediated prevention of post myocardial infarction ruptures
Background:Cardiovascular disease is a leading cause of death worldwide, claiming the lives of an estimated 17 million people annually. Myocardial infarctions (MI), or heart attacks, are a leading cause of mortality and morbidity. Complications following MI include maladaptive left ventricle (LV) tissue remodeling and cardiac rupture. Cardiac ruptu...
Annexin and its Use to Treat Inflammatory Disorders
Background:Sepsis is a complex clinical syndrome resulting from a harmful host response to infection characterized by the production of tumor necrosis factor–α (TNF-α), a pro-inflammatory cytokine, which has been shown to be one of the main mediators of cardiovascular dysfunction. Cardiovascular dysfunction is common in patients w...
Cell Culture Supplements for Generating Mature, Functional, Stabilized Blood Vessels In Vitro
Background: The difficulty in generating complex functional blood vessels in vitro has been an important limitation to the adoption and application of complex cell based models for functional screening and drug discovery. While the formation of endothelial tubes is well known within the academic literature, the ability to generate integrated vessel...
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