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Search Term: diagnostics

Technologies


High Precision Radiostereometric Analysis (RSA) System for Monitoring Micro-Movement in Orthopedic Implants
Background:Over 400,000 people per year in the United States undergo joint replacement surgery comprising a range of implant types and locations. These surgeries include the hip, knee, spine and digital/wrist. It has been well established that short-term micromotion at the implant-bone interface can be a strong predictor of long-term implant loosen...
New Powerful Tool for Monitoring of Kinase Activity
Background:In the cellular signalling network, many enzymes and receptors are activated (phosphorylated) or deactivated (dephosphorylated) by protein kinases. As a result of these modifications, the function of the protein may change. Many disease processes including cancer, heart disease, diabetes, autoimmune and chronic inflammatory diseases are ...
Electrochemical Biosensor for the Detection of HIV Enzymes
Background:Globally, there are 33 million people living with HIV. The earliest symptoms of HIV infection occur when your body begins to form antibodies to the virus between six weeks and three months after infection with the HIV virus. Approximately, 22 million HIV tests are carried out every year in the US. Only by being tested for HIV can you kno...
Ghrelin Analogues as Molecular Imaging Probes
Background: Human Growth Hormone Secretagogue Receptor (GHSR), a member of the G Protein-Coupled Receptors (GPCR) family, is mainly expressed in the hypothalamus, pituitary cells and a number of peripheral tissues. Expression of the GHSR has been reported in various types of tumors, including breast carcinomas, prostate cancer cell lines, ovarian t...
Establishment of Serum Tumor Marker in Mouse Prostate Cancer Model Studies
Background: Prostate cancer is the most common cancer in adult men in North America. A number of genetically engineered (GE) mouse models exist for basic and preclinical prostate cancer research. However, until now, no in vivo serum biomarker has been available to better understand, evaluate and demonstrate the efficacy of new therapies or drugs. I...
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