Technologies

EGFR Antagonist-mediated Prevention of Post Myocardial Infarction Ruptures

Cardiovascular disease is a leading cause of death worldwide, claiming the lives of an estimated 17 million people annually. Myocardial infarctions (MI), or heart attacks, are a leading cause of mortality and morbidity. Complications following MI include maladaptive left ventricle (LV) tissue remodeling and cardiac rupture.

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Peptides Targeting EGFL7, a Critical Player in Angiogenesis

Epidermal growth factor-like 7 (EGFL7) is an endothelial cell secreted protein whose expression is restricted to actively remodeling vascular endothelium. It is critical for vascular tube formation during angiogenesis through localizing to the extracellular matrix (ECM) at the basal surface of endothelial cells and promoting endothelial cell adhesion. In adults, expression of EGFL7 is detected only at sites of active angiogenesis during wound repair, in the pregnant uterus and in tumors.

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Food-Grade Bacteria Species to Detoxify and Remove Heavy Metals from Humans

There are many heavy metals in our environment, both naturally and from pollution. The term “heavy metal” applies to a group of metals with similar chemical properties. Some of these, including copper, iron and zinc, play important roles in our bodies, while others can have toxic effects.

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miR-195 Antagomir Treatment of Sepsis

MicroRNAs (miRNAs) are small non-coding RNA molecules encoded by eukaryotic nuclear DNA, on average 22 nucleotides long, that function in transcriptional and post-transcriptional regulation of gene expression via base-pairing with complementary sequences within mRNA molecules, usually resulting in gene silencing via translational repression or target degradation.

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The Desired Sensation Level Multi-stage [i/o] Algorithm

Tech ID: TP-W-AD-005 Background The Desired Sensation Level: DSL [i/o] algorithm was released to manufacturers in the late 1990s in the form of a dynamic loadable/linked library (DLL). We appreciate your support and want you to know that the money that we have received from manufacturers in the form of license fees for the DLL

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Treatment of Compartment Syndrome

Acute limb compartment syndrome is a potentially devastating complication of musculoskeletal trauma characterized by an increase in pressure within a closed osseofascial compartment resulting in muscle threatening and ultimately limb threatening ischemia.

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A Humanized Monoclonal Antibody to CD11d

Traumatic injuries to the brain and spinal cord are a leading cause of death among young people. Patients who are fortunate to survive the initial injury often deal with lifelong neurological impairment. With incident rates on the rise, TBI and SCI are poised to become a major contributor to the global epidemiological and economic burden among traumatic injuries.

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DNA Methylation Assay for Diagnosis and Screening of Prostate Cancer

Prostatic adenocarcinoma is the most commonly diagnosed non-cutaneous cancer for men in the United States. The incidence is likely to continue to increase as people survive longer and more middle-aged men undergo routine screening for the disease.

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Time-resolved Dynamic Angiographic Computed Tomography (TRD-ACT)

The clinical gold standard for assessing the functional significance of a coronary artery stenosis is the invasive fractional flow reserve (FFR) technique, in which a specialized catheter is advanced to the culprit artery with aids of fluoroscopy to measure the flow pressure gradient across a plaque during maximal hyperemia.

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Biomarker Profile to Predict Post-Traumatic Distress and Chronic Pain

A robust three protein-based biomarker panel blood test to predict chronic pain and categorize individuals into three recovery trajectories.

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For Industry

We work with a wide range of industry verticals to help overcome their technical challenges and/or open new and exciting market opportunities. Our team is dedicated to helping both industry and the inventor(s) find the solution that could make a difference to a company and a community.

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