Technologies

Traumatic injuries to the brain and spinal cord are a leading cause of death among young people. Patients who are fortunate to survive the initial injury often deal with lifelong neurological impairment. With incident rates on the rise, TBI and SCI are poised to become a major contributor to the global epidemiological and economic burden among traumatic injuries.

A robust state-of-the-art method to manipulate the microbiome.

Bacterial vaginosis (BV) is the most common vaginal condition, affecting an estimated 30% of women at any given time. While many women remain asymptomatic, when signs and symptoms do arise they include an elevated vaginal pH>4.5, discharge, and malodour due to amines. BV is also associated with a number of co-morbidities, including increased transmission and acquisition of HIV and other sexually transmitted infections, and increased risk of preterm labour.

Researchers at Western University have identified a mutations in S. aureus purine biosynthesis pathway that contribute to its virulence. The current invention opens up alternate treatment and target mechanisms for hard to treat S. aureus and MRSA.

Immunohistochemistry is a routine method for evaluating the distribution of antigens in microscopic tissue samples. For example, visualization of smooth muscle actin in histology is commonly used to study vascular physiology, understand disease progression and/or visualize organ development.

A yeast model for high throughput drug and small molecule screening for ALS and Distal Myopathy-2.