Technologies

Beta-amyloid plaque elimination throughout the brain with a gene therapy vector allowing for widespread therapeutic protein dissemination Background A limitation of viral‑mediated gene therapy for neurological diseases is the necessity for a focal injection of virus with limited ability to transduce cells across the entire brain away from the focal point of injection. What is

An intracavitary bladder brachytherapy applicator to enable precise control over bladder geometry for optimal radiotherapy delivery Background Brachytherapy is an alternative or complementary radiotherapy technique to external radiation that involves the placement of a radioactive source in close contact with the tumour. It is considered a standard of care for multiple pelvic cancers including cervical,

Background With nearly 642 million people globally projected to live with diabetes in the year 2040, the risk for developing diabetes-related complications will drastically increase. Diabetes mellitus (DM) is a chronic degenerative metabolic disease that is characterized by sustained hyperglycemia. Hyperglycemia correlates with a number of DM-related complications and is one of the preeminent factors

Tech ID: L-21-011 Background HPV-driven (HPV+) head and neck squamous cell carcinoma (HNSCC) is the fastest rising cancer in North America. While cure rates can be high, around 20% of patients recur after primary treatment. Current multimodal treatment regimens are historically derived from clinical trials for the more aggressive HPV-negative HNSCC and may be more

Tech ID: L-20-002 Background HPV+ HNSCC (head and neck squamous cell carcinoma) is increasing in occurrence in the HNSCC population around the world. Although there are numerous HPV negative HNSCC cell lines that have been established and that are used as models of HPV negative disease, there is a lack of HPV+ cell lines models

Tech ID: L-21-003 Background Contrast agent (CA) administration to a patient is a frequent prerequisite for medical imaging. For example, in heart imaging, the elimination of gadolinium contrast agent (CA) injections and manual segmentation are crucial for ischemic heart disease (IHD) diagnosis and treatment. In the clinic, CA-based late gadolinium enhancement (LGE) imaging and manual

Sepsis is a complex clinical syndrome resulting from a harmful host immune response to infection characterized by the production of tumor necrosis factor-α (TNF-α), a pro-inflammatory cytokine, which has been shown to be one of the main mediators of cardiovascular dysfunction.

There are many heavy metals in our environment, both naturally and from pollution. The term “heavy metal” applies to a group of metals with similar chemical properties. Some of these, including copper, iron and zinc, play important roles in our bodies, while others can have toxic effects.

Tech ID: TP-W-AD-005 Background The Desired Sensation Level: DSL [i/o] algorithm was released to manufacturers in the late 1990s in the form of a dynamic loadable/linked library (DLL). We appreciate your support and want you to know that the money that we have received from manufacturers in the form of license fees for the DLL

Acute limb compartment syndrome is a potentially devastating complication of musculoskeletal trauma characterized by an increase in pressure within a closed osseofascial compartment resulting in muscle threatening and ultimately limb threatening ischemia.